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For dogs housed at Texas kennels, age and fecal score are important factors for screening for subclinical Giardia infections.

A new form of tumor infiltrating lymphocyte (TIL) therapy, a form of personalized cancer immunotherapy, dramatically improved the treatment's effectiveness in patients with metastatic gastrointestinal cancers, according to results of a clinical trial. The findings offer hope that this therapy could be used to treat a variety of solid tumors, which has so far eluded researchers developing cell-based therapies.

By integrating powerful 3D imaging technology with advanced computation, researchers can capture gaze direction information from tens of thousands of surface points on the eye instead of about a dozen used by conventional eye-tracking methods. The technique could boost eye-tracking accuracy in a variety of fields ranging from the entertainment industry to medical research and industrial engineering.

Mpox has the potential to become a significant global health threat if taken too lightly, according to scientists.

A new study has found that children exposed to higher levels of air pollution in early and mid childhood have weaker connections between key brain regions. The findings highlight the potential impact of early exposure to air pollution on brain development.

A new article outlines a new tool that measures blood inflammation as a marker for poor CAR T therapy outcomes.

A team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumors in chicken eggs and analyzing their proteins. The team has combined these two techniques to identify and test a drug for a young patient's tumor in time to be used for their treatment. Their success in finding a new drug for the patient shows how the study of proteins, known as proteomics, can be a valuable complement to the established study of genes (genomics) in real-time cancer therapies.

Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat 'triple negative' breast cancer subtype, according to a preclinical study. The discovery could lead to new dietary and pharmaceutical strategies against breast and other cancers.

Public awareness of the link between drinking alcohol and an elevated risk of cancer has grown since last fall, with 55% of U.S. adults saying that regularly consuming alcohol increases your chances of later developing cancer, according to a new survey.

Medical imaging experts are adept at solving common optical illusions, according to new research. The research is the first to show that people can be trained to do better at solving visual illusions, which was previously thought to be near-impossible. The study shows that medical imaging experts are particularly accurate at judging the size of objects in common optical illusions. In other words, they also literally see better in everyday life!

Nearly 40% of patients diagnosed with type 2 diabetes imperil their health by stopping their medication within the first year, diabetes experts warn.

Human thermoregulation limits are lower than previously thought, indicating that some regions may soon experience heat and humidity levels exceeding safe limits for survival. The study underscores the urgent need to address climate change impacts on human health, providing vital data to inform public health strategies and climate models.

A trial of 648 patients found that the new automated method and intervention strategy resulted in nearly four times as many diagnoses and treatment plans for high blood pressure compared with traditional office-based health care visits.

AI mental health apps may offer a cheap and accessible way to fill the gaps in the overstretched U.S. mental health care system, but ethics experts warn that we need to be thoughtful about how we use them, especially with children.

Fear of emotions among couples with PTSD is associated with unproductive communication, according to a new study.

People breathing contaminated air over the course of years are at greater risk of developing numerous diseases. This is thought to be due to highly reactive components in particulate matter, which affect biological processes in the body. However, researchers have now shown that precisely these components disappear within hours and that previous measurements therefore completely underestimate the quantities in which they are present.

A newly developed blood test for Alzheimer's disease not only aids in the diagnosis of the neurodegenerative condition but also indicates how far it has progressed, according to a new study.

Researchers have developed new AI models that can vastly improve accuracy and discovery within protein science. Potentially, the models will assist the medical sciences in overcoming present challenges within, e.g. personalised medicine, drug discovery, and diagnostics.

As warehouses go, nuclei are more like libraries than bank vaults. Too many cellular components need access to the genome to lock it down like Fort Knox. Instead, large groupings of more than 1,000 individual protein molecules called nuclear pore complexes (NPCs) pepper the dividing membrane, serving as gateways for materials and messages entering and exiting the nucleus. While the basic need for this shuttle service is constant, scientists have shown that cells dynamically adjust their amounts of NPCs like a retail store opening more or fewer checkout lines throughout the day. Scientists now reveal the results of screening the entire human genome to find factors influencing how many NPCs are assembled.

A recent study finds most critically injured patients can recover with less supplemental oxygen than has previously been suggested.

New research reveals that lower proportions of specific sleep stages are associated with reduced brain volume in regions vulnerable to the development of Alzheimer's disease over time.

A new artificial intelligence tool could aid in limiting or even prevent pandemics by identifying animal species that may harbor and spread viruses capable of infecting humans. The machine learning model analyzes host characteristics and virus genetics to identify potential animal reservoirs and geographic areas where new outbreaks are more likely to occur.

A new study on the genetic causes of the PTEN Hamartoma Tumour Syndrome (PHTS) has found that inhibitors of the PI3ka pathway, commonly used as anticancer drugs, are also effective against this disease, reducing the extent of vascular malformations and lesion-associated pain in animal models. The research suggests the repurposing of these drugs may offer a new hope for PHTS patients, especially at younger ages.

Inhaling dust particles from the Red Planet over long periods of time could put humans at risk of developing respiratory issues, thyroid disease and other health problems.

New findings indicate that while the rate of marathon runners who suffer cardiac arrests remained unchanged, their chance for survival is twice what it was in the past. Now, far fewer marathon runners who suffer cardiac arrest are dying of it.

Investigators have uncovered how resistance to chemotherapies may occur in some cancers. Researchers focused on a pathway that harnesses reactive oxygen species (ROS) to kill cancer cells. The study found that mutations to VPS35, a key player in this pathway, can prevent chemotherapy-induced cell death. These results could help pinpoint treatment-resistant tumors.

A new study found that over half of US adults experienced some form of discrimination, and individuals with high exposure to discrimination have more than five times the chances of screening positive for depression, and five times the chances of screening positive for anxiety. Compared to adults who do not experience discrimination, adults who do experience this mistreatment have nearly nine times the odds of screening positive for both depression and anxiety.

The new study reveals a remarkable way that cells keep us safe from transposable elements (TEs) gone wild. The researchers found that cells have taken advantage of an entire protein network to repress TE activity and keep themselves healthy.

A new 3D printed customizable hydrogel performed well in preclinical trials with several different types of meniscal tears.

Cold water immersion for seven days significantly improves cellular resilience and autophagic function, helping cells manage stress better. This adaptation could enhance health and longevity, potentially preventing diseases and slowing aging at a cellular level.

Roughly one out of three women ages 14-49 in the United States develop a vaginal bacterial imbalance known as bacterial vaginosis (BV) during their lifetime. BV is characterized by unpleasant odors, and potentially painful side effects, as well as the risk of associated health issues later in life. More than half of the patients who seek medical care do not respond to the first-line treatment, the antibiotic metronidazole, leading to recurrence. Now researchers have developed a simple DNA PCR-based lab test -- built on a more detailed genetic analysis of the main group of bacterial organisms that cause the infection -- to help clinicians prescribe the right medicine for each patient.

The finding of a new study could advance the development of new drugs that block or open such signaling channels to treat conditions as varied as epilepsy and some intellectual disorders.

Researchers show that a cocktail of growth factors reversed would-be lethal cell damage in mice with anthrax, suggesting that this approach could be adapted for use in patients.

Leveraging the power of AI and machine learning technologies, researchers developed a more effective model for predicting how patients with muscle-invasive bladder cancer will respond to chemotherapy. The model harnesses whole-slide tumor imaging data and gene expression analyses in a way that outperforms previous models using a single data type.

Scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility. PET imaging shows that the brain increases dopamine production when completing cognitively demanding tasks, and that the more dopamine released, the more efficiently the tasks are completed. Armed with this information, physicians may soon be able to develop more precise treatment strategies for neurological and psychiatric disorders.

Researchers show that the immune system can recognize and control the latent stage of the parasite Toxoplasma gondii, a finding that can inform the study of latency in other infections of the nervous system.

Researchers have created a way to see your family tree as a movie rather than a still portrait by tracing where your ancestors moved across the globe over time. The statistical method can also be used to model disease spread and studying how animals move through geographic regions.

The way teachers manage classroom discussion with pupils plays a key role in the teaching of writing, a new study shows.

New research strongly suggests that Kawasaki disease is caused by a single respiratory virus that is yet to be identified. Findings contradict the theory that many different pathogens or toxins could cause this disease that can lead to serious cardiac complications in young children.

Researchers have conducted groundbreaking research on memristor-based brain-computer interfaces (BCIs). This research presents an innovative approach for implementing energy-efficient adaptive neuromorphic decoders in BCIs that can effectively co-evolve with changing brain signals.

Researchers reveal the way our legs adapt to fast movements. When people hop at high speeds, key muscle fibers in the calf shorten rather than lengthen as forces increase, which they call 'negative stiffness.' This counterintuitive process helps the leg become stiffer, allowing for faster motion. The findings could improve training, rehabilitation, and even the design of prosthetic limbs or robotic exoskeletons.

People living with Long COVID often feel dismissed, disbelieved and unsupported by their healthcare providers, according to a new study.

A research team has investigated structural changes in kidneys of patients with hypertension and type 2 diabetes. The results show that high blood pressure can lead to abnormalities in the podocytes, specialized cells in the renal filter, even without other pre-existing conditions such as diabetes. The results underline the importance of early detection and consistent treatment of high blood pressure in order to prevent kidney damage.

People with dementia can enjoy productive and rewarding working lives in the digital era, contrary to the widespread stereotype that dementia is incompatible with the use of modern technology, according to new research.

Wearable mobile health technology could help people with Type 2 Diabetes (T2D) to stick to exercise regimes that help them to keep the condition under control, a new study reveals. An international team studied the behavior of recently-diagnosed T2D patients in Canada and the UK as they followed a home-based physical activity program, with some participants wearing a smartwatch paired with a health app on their smartphone.

The reuse of human urine would allow for the production of sustainable fertilizers for urban agriculture, with significant environmental benefits, a new study concludes. The research evaluates the environmental impact of nitrogen recovery from the yellow waters of buildings. In addition to promoting sustainable agriculture, it would reduce carbon dioxide emissions and water consumption.

The increasing number of people with eating disorders and a lack of national guidance for support teams has led to researchers calling for a new national strategy that includes specific guidance to support the remote delivery of eating disorder services.

In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers have now discovered that these skeletal cells do not just differ in their developmental origin, but also in their gene regulation -- which may be a key to the vertebrates' evolutionary success story.

A machine learning algorithm was able to correctly identify in 97 cases out of 100 whether or not an individual had Celiac disease based on their biopsy, new research has shown. The AI tool, which has been trained on almost 3,400 scanned biopsies from four hospitals, could speed up diagnosis of the condition and take pressure off stretched healthcare resources, as well as improving diagnosis in developing nations, where shortages of pathologists are severe.

Researchers reveal critical mechanism behind idiopathic pulmonary fibrosis.

Researchers have discovered a groundbreaking use of terahertz (THz) imaging to visualize cochlear structures in mice, offering non-invasive, high-resolution diagnostics. By creating 3D reconstructions, this technology opens new possibilities for diagnosing hearing loss and other conditions. THz imaging could lead to miniaturized devices, like THz endoscopes and otoscopes, revolutionizing diagnostics for hearing loss, cancer, and more. With the potential to enhance diagnostic speed, accuracy, and patient outcomes, THz imaging could transform medical practices.

Previously unknown access points in cell membrane proteins have been discovered, enabling laboratory-developed drugs to modify cell function. The discovery was made possible through computer simulations with an unprecedented level of detail. The results are available online to support the development of new, targeted drugs for a wide range of diseases.

Researchers conducted the first clinical trial of an AI-powered therapy chatbot and found that, on average, people with diagnosed mental disorders experienced clinically significant improvements in their symptoms over eight weeks, according to new results. Users engaged with the software, known as Therabot, through a smartphone app and reported that interactions were comparable to working with a mental-health professional. The researchers conclude that while AI-powered therapy is in critical need of clinician oversight, it has the potential to provide real-time support for the many people who lack regular or immediate access to a professional.

To encourage scientists to speak up when people misuse science to serve political agendas, biology professor Mark Peifer of the University of North Carolina at Chapel Hill argues that eugenics should be included in college genetics curriculums.

Researchers have found that the clinical application of BCR::ABL1 digital PCR can reliably quantify stable deep molecular remission of chronic myeloid leukemia (CML), which will help to determine for which patients chronic drug treatment could potentially be discontinued. This transcript that is unique for CML is more sensitive and accurate than the current standard, real-time quantitative PCR (RT-qPCR), for detecting ultralow levels of residual leukemic disease.

Most haptic devices only deliver feedback as simple vibrations. New device applies dynamic forces in any direction to simulate a more realistic sense of touch. Small, lightweight device can enhance virtual reality, help individuals with visual impairments, provide tactile feedback for remote health visits and more.

People living in more disadvantaged neighborhoods may be more likely to develop dementia than people living in neighborhoods with fewer disadvantages, according to a new study. The study does not prove that neighborhood factors cause dementia; it only shows an association.

People who have early signs of heart problems may also have changes in brain health that can be early signs of dementia, such as loss of brain volume, according to a meta-analysis. The meta-analysis does not prove that early heart problems cause loss of brain cells; it only shows an association.

A tiny magnetic robot which can take 3D scans from deep within the body, that could revolutionize early cancer detection, has been developed by researchers. The team say this is the first time it has been possible to generate high-resolution three-dimensional ultrasound images taken from a probe deep inside the gastrointestinal tract, or gut.

A new study indicates that when healthy adults pair an eight-hour eating window with regular exercise, they lose more fat -- without sacrificing lean muscle -- compared to exercise alone.